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Best Cruises from San Francisco

We've found the Best Cruises from San Francisco for the best prices! Easily compare sailings and find out when to book with our unique cruise search.

Very good price

Compared to other cruises

18 Night Panama Canal
Norwegian Joy
3.2 "Good"

PORTS

San Francisco; San Francisco; Los Angeles; Cabo San Lucas; Acapulco; Puerto Quetzal, G... Miami, Florida

SAIL DATE:   Oct 02, 2025   -   Oct 20, 2025

Interior

$899 $49/night
Price Curve

Oceanview

$1198 $66/night
Price Curve

Balcony

$1698 $94/night
Price Curve

Suite

$2099 $116/night
Price Curve

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Very good price

Compared to other cruises

11 Night Mexico
Ruby Princess
3.8 "Good"

PORTS

San Francisco; Manzanillo; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Francisco

SAIL DATE:   Nov 15, 2025   -   Nov 26, 2025

Interior

$672 $61/night
Price Curve

Oceanview

$747 $67/night
Price Curve

Balcony

$972 $88/night
Price Curve

Suite

$1472 $133/night
Price Curve

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Very good price

Compared to other cruises

16 Night Pacific Coastal
Ruby Princess
3.8 "Good"

PORTS

San Francisco; Hilo; Honolulu; Kauai (Nawiliwili); Kahului, Maui; Ensenada; San Francisco

SAIL DATE:   Dec 01, 2025   -   Dec 17, 2025

Interior

$994 $62/night
Price Curve

Oceanview

$1053 $65/night
Price Curve

Balcony

$1644 $102/night
Price Curve

Suite

$2144 $134/night
Price Curve

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Very good price

Compared to other cruises

11 Night Mexico
Ruby Princess
3.8 "Good"

PORTS

San Francisco; Manzanillo; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Francisco

SAIL DATE:   Sep 24, 2025   -   Oct 05, 2025

Interior

$722 $65/night
Price Curve

Oceanview

$822 $74/night
Price Curve

Balcony

$1072 $97/night
Price Curve

Suite

$1772 $161/night
Price Curve

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Very good price

Compared to other cruises

11 Night Mexico
Ruby Princess
3.8 "Good"

PORTS

San Francisco; Manzanillo; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Francisco

SAIL DATE:   Oct 19, 2025   -   Oct 30, 2025

Interior

$821 $74/night
Price Curve

Oceanview

$901 $81/night
Price Curve

Balcony

$1122 $102/night
Price Curve

Suite

$1671 $151/night
Price Curve

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Very good price

Compared to other cruises

11 Night Mexico
Ruby Princess
3.8 "Good"

PORTS

San Francisco; Manzanillo; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Francisco

SAIL DATE:   Jan 18, 2026   -   Jan 29, 2026

Interior

$821 $74/night
Price Curve

Oceanview

$924 $84/night
Price Curve

Balcony

$1421 $129/night
Price Curve

Suite

$1771 $161/night
Price Curve

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Very good price

Compared to other cruises

16 Night Panama Canal
Carnival Legend
3.8 "Good"

PORTS

San Francisco; Cabo San Lucas; Puntarenas, Costa Rica; Cartagena, Spain; Grand Cayman; Galveston

SAIL DATE:   Oct 06, 2025   -   Oct 22, 2025

Interior

$1130 $70/night
Price Curve

Oceanview

$1734 $108/night
Price Curve

Balcony

not available
Price Curve

Suite

$4106 $256/night
Price Curve

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-6%

18 Night Panama Canal
Norwegian Encore
3.3 "Good"

PORTS

San Francisco; Los Angeles; Cabo San Lucas; Puerto Vallarta; Manzanillo; Acapulco; Pue... Miami, Florida

SAIL DATE:   Oct 21, 2025   -   Nov 08, 2025

Interior

$1007 $55/night
Price Curve

Oceanview

$1386 $77/night
Price Curve

Balcony

$1756 $97/night
Price Curve

Suite

$2029 $112/night
Price Curve

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Discover the best cruises from San Francisco with our ultra-refined cruise search. Plus, save up to 70% off when you use our unmatched price prediction and free automatic price alerts! With cruisewatch.com, it’s simpler than ever to find your perfect cruise from San Francisco and make it a vacation to remember. Explore expert tips and advice for all cruise lines, destinations, and cruise styles and set sail for savings from San Francisco! Pack your bags and get ready to go - your dream cruise is now closer and better than ever!