Best Cruises from San Francisco
We've found the Best Cruises from San Francisco for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
18 Night Panama Canal
PORTS
San Francisco; San Francisco; Los Angeles; Cabo San Lucas; Acapulco; Puerto Quetzal, G... Miami, Florida
SAIL DATE: Oct 02, 2025 - Oct 20, 2025
11 Night Mexico
PORTS
San Francisco; Manzanillo; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Francisco
SAIL DATE: Nov 15, 2025 - Nov 26, 2025
11 Night Mexico
PORTS
San Francisco; Manzanillo; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Francisco
SAIL DATE: Sep 24, 2025 - Oct 05, 2025
11 Night Mexico
PORTS
San Francisco; Manzanillo; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Francisco
SAIL DATE: Mar 07, 2026 - Mar 18, 2026
11 Night Mexico
PORTS
San Francisco; Manzanillo; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Francisco
SAIL DATE: Jan 18, 2026 - Jan 29, 2026
16 Night Panama Canal
PORTS
San Francisco; Cabo San Lucas; Puntarenas, Costa Rica; Cartagena, Spain; Grand Cayman; Galveston
SAIL DATE: Oct 06, 2025 - Oct 22, 2025
Interior
$1060 $66/night
Oceanview
$1624 $101/night
Balcony
not available
Suite
not available
11 Night Mexico
PORTS
San Francisco; Manzanillo; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Francisco
SAIL DATE: Oct 19, 2025 - Oct 30, 2025
11 Night Alaska
PORTS
San Francisco; Ketchikan; Juneau, Alaska; Skagway; Victoria; San Francisco
SAIL DATE: Sep 13, 2025 - Sep 24, 2025
17 Night Panama Canal
PORTS
San Francisco; Mazatlan; Puerto Vallarta; Puerto Quetzal, Guatemala; Puntaren... Ft. Lauderdale, Florida
SAIL DATE: Aug 31, 2026 - Sep 17, 2026
11 Night Mexico
PORTS
San Francisco; Manzanillo; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Francisco
SAIL DATE: Dec 15, 2026 - Dec 26, 2026
