Best Cruises from San Francisco
We've found the Best Cruises from San Francisco for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
16 Night Panama Canal
PORTS
San Francisco; Puerto Vallarta; Puerto Quetzal, Guatemala; Puntarenas, Costa... Ft. Lauderdale, Florida
SAIL DATE: Dec 07, 2025 - Dec 23, 2025
16 Night Pacific Coastal
PORTS
San Francisco; Hilo; Honolulu; Kauai (Nawiliwili); Kahului, Maui; Ensenada; San Francisco
SAIL DATE: Dec 01, 2025 - Dec 17, 2025
16 Night Pacific Coastal
PORTS
San Francisco; Kauai (Nawiliwili); Honolulu; Kahului, Maui; Kona, Hawaii, Us; Ensenada; San Francisco
SAIL DATE: Dec 17, 2025 - Jan 02, 2026
Discover the best cruises from San Francisco with our ultra-refined cruise search. Plus, save up to 70% off when you use our unmatched price prediction and free automatic price alerts! With cruisewatch.com, it’s simpler than ever to find your perfect cruise from San Francisco and make it a vacation to remember. Explore expert tips and advice for all cruise lines, destinations, and cruise styles and set sail for savings from San Francisco! Pack your bags and get ready to go - your dream cruise is now closer and better than ever!