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Best South America Cruises

Find the Best South America Cruises for you. Easily compare prices and find out when to book your dream vacation to South America with our cruise search.

Very good price

Compared to other cruises

7 Night South America
MSC Seaview
3.1 "Good"

PORTS

Santos (Sao Paulo), Brazil; Buzios, Brazil; Salvador De Bahia, Brazil; Mac... Santos (Sao Paulo), Brazil

SAIL DATE:   Mar 28, 2026   -   Apr 04, 2026

Interior

$619 $88/night
Price Curve

Oceanview

$789 $112/night
Price Curve

Balcony

$949 $135/night
Price Curve

Suite

$1499 $214/night
Price Curve

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Very good price

Compared to other cruises

7 Night South America
MSC Preziosa
3.2 "Good"

PORTS

Buenos Aires; Santos (Sao Paulo), Brazil; Camboriu Brazil; Punta Del Este, Uruguay; Buenos Aires

SAIL DATE:   Mar 19, 2026   -   Mar 26, 2026

Interior

$638 $91/night
Price Curve

Oceanview

$808 $115/night
Price Curve

Balcony

$928 $132/night
Price Curve

Suite

$1398 $199/night
Price Curve

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Very good price

Compared to other cruises

7 Night South America
MSC Preziosa
3.2 "Good"

PORTS

Buenos Aires; Santos (Sao Paulo), Brazil; Camboriu Brazil; Punta Del Este, Uruguay; Buenos Aires

SAIL DATE:   Mar 12, 2026   -   Mar 19, 2026

Interior

$638 $91/night
Price Curve

Oceanview

$788 $112/night
Price Curve

Balcony

$928 $132/night
Price Curve

Suite

$1398 $199/night
Price Curve

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Very good price

Compared to other cruises

7 Night South America
MSC Lirica
2.9 "Nice"

PORTS

Piraeus; Izmir (Ephesus) Turkey; Istanbul; Corfu; Bari, Italy; Piraeus

SAIL DATE:   Jan 19, 2026   -   Jan 26, 2026

Interior

$559 $79/night
Price Curve

Oceanview

$699 $99/night
Price Curve

Balcony

$989 $141/night
Price Curve

Suite

$1189 $169/night
Price Curve

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Very good price

Compared to other cruises

8 Night South America
MSC Preziosa
3.2 "Good"

PORTS

Santos (Sao Paulo), Brazil; Montevideo; Buenos Aires; Punta Del Este, Urug... Santos (Sao Paulo), Brazil

SAIL DATE:   Jan 17, 2026   -   Jan 25, 2026

Interior

$808 $101/night
Price Curve

Oceanview

$998 $124/night
Price Curve

Balcony

$1198 $149/night
Price Curve

Suite

$1758 $219/night
Price Curve

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Very good price

Compared to other cruises

7 Night South America
MSC Preziosa
3.2 "Good"

PORTS

Santos (Sao Paulo), Brazil; Camboriu Brazil; Punta Del Este, Uruguay; Buen... Santos (Sao Paulo), Brazil

SAIL DATE:   Mar 01, 2026   -   Mar 08, 2026

Interior

$708 $101/night
Price Curve

Oceanview

$878 $125/night
Price Curve

Balcony

$1038 $148/night
Price Curve

Suite

$1528 $218/night
Price Curve

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Very good price

Compared to other cruises

7 Night South America
MSC Preziosa
3.2 "Good"

PORTS

Santos (Sao Paulo), Brazil; Camboriu Brazil; Punta Del Este, Uruguay; Buen... Santos (Sao Paulo), Brazil

SAIL DATE:   Feb 08, 2026   -   Feb 15, 2026

Interior

$718 $102/night
Price Curve

Oceanview

$888 $126/night
Price Curve

Balcony

$1048 $149/night
Price Curve

Suite

$1538 $219/night
Price Curve

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Very good price

Compared to other cruises

7 Night South America
MSC Preziosa
3.2 "Good"

PORTS

Santos (Sao Paulo), Brazil; Camboriu Brazil; Punta Del Este, Uruguay; Buen... Santos (Sao Paulo), Brazil

SAIL DATE:   Mar 08, 2026   -   Mar 15, 2026

Interior

$718 $102/night
Price Curve

Oceanview

$888 $126/night
Price Curve

Balcony

$1048 $149/night
Price Curve

Suite

$1538 $219/night
Price Curve

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Very good price

Compared to other cruises

7 Night South America
MSC Preziosa
3.2 "Good"

PORTS

Santos (Sao Paulo), Brazil; Camboriu Brasil; Punta Del Este, Uruguay; Buen... Santos (Sao Paulo), Brazil

SAIL DATE:   Mar 15, 2026   -   Mar 22, 2026

Interior

$718 $102/night
Price Curve

Oceanview

$888 $126/night
Price Curve

Balcony

$1048 $149/night
Price Curve

Suite

$1538 $219/night
Price Curve

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Very good price

Compared to other cruises

7 Night South America
MSC Preziosa
3.2 "Good"

PORTS

Santos (Sao Paulo), Brazil; Camboriu Brazil; Punta Del Este, Uruguay; Buen... Santos (Sao Paulo), Brazil

SAIL DATE:   Mar 22, 2026   -   Mar 29, 2026

Interior

$718 $102/night
Price Curve

Oceanview

$888 $126/night
Price Curve

Balcony

$1048 $149/night
Price Curve

Suite

$1538 $219/night
Price Curve

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With cruisewatch.com, it’s easier than ever to find the best South America cruises for the best price. We use data-driven analytics to simplify the process - from finding the sailing that’s perfect for you to offering unmatched price prediction to let you know when to book. Our personalized and super-refined search engine also gives you complete control, and with free automatic price alerts, staying on top of the market is stress-free. Take advantage of our awesome features to save up to 70% off your dream South America cruise and explore our library of free resources and expert insights so you can make your South America cruise truly unforgettable!