Best South America Cruises
Find the Best South America Cruises for you. Easily compare prices and find out when to book your dream vacation to South America with our cruise search.
22 Night South America
PORTS
Miami, Florida; Cozumel, Mexico; Belize City; Santo Tomas De Cas... San Antonio, Ibiza, Balearic Islands
SAIL DATE: Nov 29, 2025 - Dec 21, 2025
25 Night South America
PORTS
Miami, Florida; Road Town, Tortola; St. John's, Antigua; Castries; Scarborough, Tobago... Miami, Florida
SAIL DATE: Nov 24, 2026 - Dec 19, 2026
25 Night South America
PORTS
Miami, Florida; St. John's, Antigua; Castries; St. George's, Grenada; Scarborough, Tob... Miami, Florida
SAIL DATE: Nov 12, 2025 - Dec 07, 2025
36 Night South America
PORTS
Miami, Florida; Great Stirrup Cay Bahamas; Willemstad; Oranjestad; Santa Marta, Colombia... Buenos Aires
SAIL DATE: Dec 19, 2026 - Jan 24, 2027
15 Night South America
PORTS
Miami, Florida; Great Stirrup Cay Bahamas; Willemstad; Oranjestad; Santa Mart... LIMAMACHU PICCHU CALLAO
SAIL DATE: Dec 19, 2026 - Jan 03, 2027
22 Night South America
PORTS
Miami, Florida; Bridgetown; Port Of Spain, Trinidad; Santarem, Brazil; Manaus; St. Geo... Miami, Florida
SAIL DATE: Nov 09, 2026 - Dec 01, 2026
Interior
not available
Oceanview
not available
Balcony
not available
Suite
$12099 $549/night
28 Night South America
PORTS
Miami, Florida; George Town, Cayman Islands; Falmouth, Jamaica; San Andres Island... Punta Arenas, Chile
SAIL DATE: Jan 13, 2028 - Feb 10, 2028
Interior
not available
Oceanview
not available
Balcony
not available
Suite
$19699 $703/night
18 Night South America
PORTS
Miami, Florida; Charlotte Amalie, St. Thomas; St. John's, Antigua; Castries; Bridgetow... Rio de Janeiro
SAIL DATE: Jan 04, 2027 - Jan 22, 2027
Interior
not available
Oceanview
not available
Balcony
not available
Suite
$12249 $680/night
18 Night South America
PORTS
Miami, Florida; Gustavia; Roseau; Bridgetown; Devils Island, French Guiana; Belem (Ic... Rio de Janeiro
SAIL DATE: Jan 06, 2026 - Jan 24, 2026
Interior
not available
Oceanview
not available
Balcony
$6399 $355/night
Suite
$10499 $583/night