Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
8 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Mazatlan; Puerto Vallarta; San Diego
SAIL DATE: Oct 18, 2025 - Oct 26, 2025
17 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Oct 09, 2025 - Oct 26, 2025
4 Night Pacific Coastal
PORTS
San Diego; Santa Barbara, California; Avalon, Catalina Island, California; Ensenada; San Diego
SAIL DATE: Oct 21, 2025 - Oct 25, 2025
7 Night Mexico
PORTS
San Diego; Ensenada; Cabo San Lucas; Puerto Vallarta; San Diego
SAIL DATE: Oct 04, 2025 - Oct 11, 2025
Interior
not available
Oceanview
$1034 $147/night
Balcony
$1234 $176/night
Suite
$2334 $333/night
16 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; Mazatlan; Puerto Quetzal, Guatemala; Puntarenas, Costa Ric... Fort Lauderdale
SAIL DATE: Oct 04, 2025 - Oct 20, 2025
Interior
$2916 $182/night
Oceanview
not available
Balcony
not available
Suite
not available