Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
7 Night Mexico
PORTS
San Diego; Cabo San Lucas; Mazatlan; Puerto Vallarta; San Diego
SAIL DATE: Oct 26, 2025 - Nov 02, 2025
14 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Avalon, Catalin... San Diego
SAIL DATE: Oct 25, 2025 - Nov 08, 2025
14 Night Mexico
PORTS
San Diego; Ensenada; San Francisco; San Francisco; Santa Barbara, California; San Diego; Pu... San Diego
SAIL DATE: Oct 11, 2025 - Oct 25, 2025
Interior
$1429 $102/night
Oceanview
$1469 $104/night
Balcony
$2029 $144/night
Suite
not available
14 Night Mexico
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Cabo San Lucas; PICHILINGU... San Diego
SAIL DATE: Oct 18, 2025 - Nov 01, 2025
14 Night Mexico
PORTS
San Diego; Ensenada; Cabo San Lucas; Puerto Vallarta; San Diego; Ensenada; San Francisco; S... San Diego
SAIL DATE: Oct 04, 2025 - Oct 18, 2025
Interior
$1549 $110/night
Oceanview
$1639 $117/night
Balcony
$2109 $150/night
Suite
not available
14 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; Acapulco; Puerto Quetzal, Guatemala; Panama City (Pct), Pan... Miami, Florida
SAIL DATE: Oct 18, 2025 - Nov 01, 2025
7 Night Mexico
PORTS
San Diego; Ensenada; Cabo San Lucas; Puerto Vallarta; San Diego
SAIL DATE: Oct 04, 2025 - Oct 11, 2025
Interior
not available
Oceanview
$1034 $147/night
Balcony
$1234 $176/night
Suite
$2334 $333/night