Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
16 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mex... Ft. Lauderdale, Florida
SAIL DATE: Jan 29, 2027 - Feb 14, 2027
8 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Mazatlan; Puerto Vallarta; San Diego
SAIL DATE: Oct 18, 2025 - Oct 26, 2025
8 Night Pacific
PORTS
San Diego; Ensenada; Santa Barbara, California; San Francisco; San Francisco; Astoria, Oregon; Vancouver
SAIL DATE: Apr 11, 2026 - Apr 19, 2026
7 Night Mexico
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego
SAIL DATE: Mar 28, 2026 - Apr 04, 2026
7 Night Mexico
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego
SAIL DATE: Apr 04, 2026 - Apr 11, 2026
7 Night Mexico
PORTS
San Diego; Cabo San Lucas; Mazatlan; Puerto Vallarta; San Diego
SAIL DATE: Mar 06, 2027 - Mar 13, 2027
7 Night Mexico
PORTS
San Diego; Cabo San Lucas; Mazatlan; Puerto Vallarta; San Diego
SAIL DATE: Mar 20, 2027 - Mar 27, 2027
7 Night Mexico
PORTS
San Diego; Cabo San Lucas; Mazatlan; Puerto Vallarta; San Diego
SAIL DATE: Mar 13, 2027 - Mar 20, 2027
26 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Puer... Miami, Florida
SAIL DATE: Feb 27, 2026 - Mar 25, 2026
27 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; Guaymas, Mexico; Topo... Miami, Florida
SAIL DATE: Feb 15, 2026 - Mar 14, 2026
Interior
$3094 $114/night
Oceanview
$3384 $125/night
Balcony
$5374 $199/night
Suite
not available