Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
14 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Puerto Vallarta... San Diego
SAIL DATE: Nov 15, 2025 - Nov 29, 2025
11 Night Mexico
PORTS
San Diego; Manzanillo; Puerto Vallarta; Mazatlan; PICHILINGUE (LA PAZ); Loreto, Mexico; Cab... San Diego
SAIL DATE: Dec 08, 2026 - Dec 19, 2026
10 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; Mazatlan; Puerto Vallarta; San Diego
SAIL DATE: Nov 28, 2026 - Dec 08, 2026
12 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Guaymas, Mexico; Topolobampo, Mexico; Lore... San Diego
SAIL DATE: Dec 06, 2025 - Dec 18, 2025
Interior
$1174 $97/night
Oceanview
$1224 $102/night
Balcony
not available
Suite
$2574 $214/night
11 Night Mexico
PORTS
San Diego; Manzanillo; Puerto Vallarta; Mazatlan; PICHILINGUE (LA PAZ); Loreto, Mexico; Cab... San Diego
SAIL DATE: Oct 20, 2026 - Oct 31, 2026
14 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; Acapulco; Puerto Quetzal, Guatemala; Panama City (Pct), Pan... Miami, Florida
SAIL DATE: Oct 18, 2025 - Nov 01, 2025
11 Night Mexico
PORTS
San Diego; Cabo San Lucas; Mazatlan; Puerto Vallarta; San Diego; Victoria; Vancouver
SAIL DATE: Mar 27, 2027 - Apr 07, 2027
14 Night Mexico
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Cabo San Lucas; PICHILINGU... San Diego
SAIL DATE: Dec 26, 2026 - Jan 09, 2027
14 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Puerto Vallarta... San Diego
SAIL DATE: Dec 20, 2025 - Jan 03, 2026
14 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Puerto Vallarta... San Diego
SAIL DATE: Dec 19, 2026 - Jan 02, 2027
