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San Diego 200 $ to 250 $ Medium ship
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Best Cruises from San Diego

We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.

Very good price

Compared to other cruises

7 Night Mexico
Serenade of the Seas
4.0 "Good"

PORTS

San Diego; La Paz; Cabo San Lucas; Ensenada; San Diego

SAIL DATE:   Oct 04, 2026   -   Oct 11, 2026

Interior

$512 $73/night
Price Curve

Oceanview

$732 $104/night
Price Curve

Balcony

$954 $136/night
Price Curve

Suite

$1659 $237/night
Price Curve

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Very good price

Compared to other cruises

7 Night Mexico
Serenade of the Seas
4.0 "Good"

PORTS

San Diego; La Paz; Cabo San Lucas; Ensenada; San Diego

SAIL DATE:   Oct 25, 2026   -   Nov 01, 2026

Interior

$522 $74/night
Price Curve

Oceanview

$722 $103/night
Price Curve

Balcony

$924 $132/night
Price Curve

Suite

$1559 $222/night
Price Curve

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Very good price

Compared to other cruises

7 Night Mexico
Serenade of the Seas
4.0 "Good"

PORTS

San Diego; Ensenada; Cabo San Lucas; La Paz; San Diego

SAIL DATE:   Oct 18, 2026   -   Oct 25, 2026

Interior

$542 $77/night
Price Curve

Oceanview

$722 $103/night
Price Curve

Balcony

$924 $132/night
Price Curve

Suite

$1579 $225/night
Price Curve

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Very good price

Compared to other cruises

14 Night Mexico
Nieuw Amsterdam
3.9 "Good"

PORTS

San Diego; Avalon, Catalina Island, California; San Francisco; San Francisco; Ensenada; San... San Diego

SAIL DATE:   Nov 01, 2025   -   Nov 15, 2025

Interior

$1119 $79/night
Price Curve

Oceanview

$1249 $89/night
Price Curve

Balcony

$1679 $119/night
Price Curve

Suite

$3499 $249/night
Price Curve

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Very good price

Compared to other cruises

4 Night Mexico
Serenade of the Seas
4.0 "Good"

PORTS

San Diego; Catalina Island; Ensenada; San Diego

SAIL DATE:   Oct 11, 2026   -   Oct 15, 2026

Interior

$319 $79/night
Price Curve

Oceanview

$419 $104/night
Price Curve

Balcony

$479 $119/night
Price Curve

Suite

$897 $224/night
Price Curve

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Very good price

Compared to other cruises

14 Night Mexico
Nieuw Amsterdam
3.9 "Good"

PORTS

San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Cabo San Lucas; PICHILINGU... San Diego

SAIL DATE:   Nov 08, 2025   -   Nov 22, 2025

Interior

$1169 $83/night
Price Curve

Oceanview

$1249 $89/night
Price Curve

Balcony

$1759 $125/night
Price Curve

Suite

$3249 $232/night
Price Curve

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Very good price

Compared to other cruises

14 Night Mexico
Nieuw Amsterdam
3.9 "Good"

PORTS

San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Cabo San Lucas; PICHILINGU... San Diego

SAIL DATE:   Oct 18, 2025   -   Nov 01, 2025

Interior

$1209 $86/night
Price Curve

Oceanview

$1289 $92/night
Price Curve

Balcony

$1799 $128/night
Price Curve

Suite

$3419 $244/night
Price Curve

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Very good price

Compared to other cruises

14 Night Mexico
Nieuw Amsterdam
3.9 "Good"

PORTS

San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Puerto Vallarta... San Diego

SAIL DATE:   Nov 15, 2025   -   Nov 29, 2025

Interior

$1209 $86/night
Price Curve

Oceanview

$1289 $92/night
Price Curve

Balcony

$1889 $134/night
Price Curve

Suite

$3419 $244/night
Price Curve

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Very good price

Compared to other cruises

4 Night Mexico
Serenade of the Seas
4.0 "Good"

PORTS

San Diego; Catalina Island; Ensenada; San Diego

SAIL DATE:   Mar 21, 2027   -   Mar 25, 2027

Interior

$339 $84/night
Price Curve

Oceanview

$439 $109/night
Price Curve

Balcony

$498 $124/night
Price Curve

Suite

$939 $234/night
Price Curve

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Very good price

Compared to other cruises

4 Night Pacific Coastal
Eurodam
4.0 "Good"

PORTS

San Diego; Avalon, Catalina Island, California; Vancouver

SAIL DATE:   Apr 20, 2026   -   Apr 24, 2026

Interior

$394 $98/night
Price Curve

Oceanview

$444 $111/night
Price Curve

Balcony

$604 $151/night
Price Curve

Suite

$994 $248/night
Price Curve

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Discover the best cruises from San Diego with our ultra-refined cruise search. Plus, save up to 70% off when you use our unmatched price prediction and free automatic price alerts! With cruisewatch.com, it’s simpler than ever to find your perfect cruise from San Diego and make it a vacation to remember. Explore expert tips and advice for all cruise lines, destinations, and cruise styles and set sail for savings from San Diego! Pack your bags and get ready to go - your dream cruise is now closer and better than ever!