Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
28 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 29, 2025
17 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 18, 2025
5 Night Pacific Coastal
PORTS
San Diego; San Francisco; Vancouver
SAIL DATE: Apr 27, 2026 - May 02, 2026
4 Night Pacific Coastal
PORTS
San Diego; Avalon, Catalina Island, California; Vancouver
SAIL DATE: Apr 20, 2026 - Apr 24, 2026
4 Night Pacific Coastal
PORTS
San Diego; Santa Barbara, California; Avalon, Catalina Island, California; Ensenada; San Diego
SAIL DATE: Oct 21, 2025 - Oct 25, 2025
11 Night Mexico
PORTS
San Diego; Manzanillo; Puerto Vallarta; Mazatlan; PICHILINGUE (LA PAZ); Loreto, Mexico; Cab... San Diego
SAIL DATE: Dec 08, 2026 - Dec 19, 2026
11 Night Mexico
PORTS
San Diego; Manzanillo; Puerto Vallarta; Mazatlan; PICHILINGUE (LA PAZ); Loreto, Mexico; Cab... San Diego
SAIL DATE: Oct 20, 2026 - Oct 31, 2026
10 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; Mazatlan; Puerto Vallarta; San Diego
SAIL DATE: Nov 28, 2026 - Dec 08, 2026
7 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego
SAIL DATE: Nov 07, 2026 - Nov 14, 2026
7 Night Pacific Coastal
PORTS
San Diego; Avalon, Catalina Island, California; San Francisco; San Francisco; Ensenada; San Diego
SAIL DATE: Nov 14, 2026 - Nov 21, 2026
