Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
17 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Oct 09, 2025 - Oct 26, 2025
7 Night Mexico
PORTS
San Diego; La Paz; Cabo San Lucas; Ensenada; San Diego
SAIL DATE: Oct 25, 2026 - Nov 01, 2026
7 Night Mexico
PORTS
San Diego; Ensenada; Cabo San Lucas; La Paz; San Diego
SAIL DATE: Oct 18, 2026 - Oct 25, 2026
7 Night Mexico
PORTS
San Diego; La Paz; Cabo San Lucas; Ensenada; San Diego
SAIL DATE: Oct 04, 2026 - Oct 11, 2026
7 Night Mexico
PORTS
San Diego; La Paz; Cabo San Lucas; Ensenada; San Diego
SAIL DATE: Jan 03, 2027 - Jan 10, 2027
7 Night Mexico
PORTS
San Diego; Catalina Island; Ensenada; Cabo San Lucas; Cabo San Lucas; San Diego
SAIL DATE: Dec 13, 2026 - Dec 20, 2026
28 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 29, 2025
4 Night Mexico
PORTS
San Diego; Catalina Island; Ensenada; San Diego
SAIL DATE: Mar 21, 2027 - Mar 25, 2027
4 Night Mexico
PORTS
San Diego; Catalina Island; Ensenada; San Diego
SAIL DATE: Oct 11, 2026 - Oct 15, 2026
13 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puntarenas, Costa Rica; Cartagena, Spain; Miami, Florida
SAIL DATE: Sep 19, 2025 - Oct 02, 2025
Interior
$1088 $83/night
Oceanview
$2237 $172/night
Balcony
$3259 $250/night
Suite
not available