Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
28 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 29, 2025
5 Night Pacific Coastal
PORTS
San Diego; San Francisco; Vancouver
SAIL DATE: Apr 27, 2026 - May 02, 2026
11 Night Mexico
PORTS
San Diego; Manzanillo; Puerto Vallarta; Mazatlan; PICHILINGUE (LA PAZ); Loreto, Mexico; Cab... San Diego
SAIL DATE: Dec 08, 2026 - Dec 19, 2026
10 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; Mazatlan; Puerto Vallarta; San Diego
SAIL DATE: Nov 28, 2026 - Dec 08, 2026
17 Night Hawaii
PORTS
San Diego; Honolulu; Kahului, Maui; Nawiliwili, Kauai; Hilo; Kona, Hawaii, Us; Ensenada; San Diego
SAIL DATE: Jan 09, 2027 - Jan 26, 2027
28 Night Hawaii
PORTS
San Diego; Cabo San Lucas; Mazatlan; Puerto Vallarta; San Diego; Victoria; Vancouver; Nawil... Vancouver
SAIL DATE: Mar 27, 2027 - Apr 24, 2027
7 Night Pacific Coastal
PORTS
San Diego; Avalon, Catalina Island, California; San Francisco; San Francisco; Ensenada; San Diego
SAIL DATE: Nov 14, 2026 - Nov 21, 2026
7 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego
SAIL DATE: Nov 21, 2026 - Nov 28, 2026
18 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Cabo San Lucas;... Vancouver
SAIL DATE: Mar 20, 2027 - Apr 07, 2027
