Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
28 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 29, 2025
24 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Oct 09, 2025 - Nov 02, 2025
29 Night Hawaii
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Guaymas, Mexico; Topolobampo, Mexico; Lore... San Diego
SAIL DATE: Dec 06, 2025 - Jan 04, 2026
Interior
$2709 $93/night
Oceanview
$2809 $96/night
Balcony
not available
Suite
$6559 $226/night
29 Night Hawaii
PORTS
San Diego; Kona, Hawaii, Us; Honolulu; Honolulu; Kahului, Maui; Hilo; Ensenada; San Diego;... San Diego
SAIL DATE: Nov 19, 2025 - Dec 18, 2025
Interior
$2734 $94/night
Oceanview
$2834 $97/night
Balcony
not available
Suite
$6074 $209/night
25 Night Hawaii
PORTS
San Diego; Avalon, Catalina Island, California; San Francisco; San Francisco; Astoria, Oreg... Vancouver
SAIL DATE: Apr 04, 2026 - Apr 29, 2026
24 Night Hawaii
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Honolulu; Kahul... San Diego
SAIL DATE: Jan 02, 2027 - Jan 26, 2027
26 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Puer... Miami, Florida
SAIL DATE: Feb 27, 2026 - Mar 25, 2026
27 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; Guaymas, Mexico; Topo... Miami, Florida
SAIL DATE: Feb 15, 2026 - Mar 14, 2026
Interior
$3094 $114/night
Oceanview
$3384 $125/night
Balcony
$6144 $227/night
Suite
not available
28 Night Hawaii
PORTS
San Diego; Cabo San Lucas; Mazatlan; Puerto Vallarta; San Diego; Victoria; Vancouver; Nawil... Vancouver
SAIL DATE: Mar 27, 2027 - Apr 24, 2027
30 Night Hawaii
PORTS
San Diego; Hilo; Kona, Hawaii, Us; Kahului, Maui; Nawiliwili, Kauai; Honolulu; Honolulu; En... San Diego
SAIL DATE: Nov 19, 2026 - Dec 19, 2026
Interior
$3289 $109/night
Oceanview
$3939 $131/night
Balcony
not available
Suite
$8089 $269/night