Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
28 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 29, 2025
29 Night Hawaii
PORTS
San Diego; Kona, Hawaii, Us; Honolulu; Honolulu; Kahului, Maui; Hilo; Ensenada; San Diego;... San Diego
SAIL DATE: Nov 19, 2025 - Dec 18, 2025
Interior
$2264 $78/night
Oceanview
$2454 $84/night
Balcony
not available
Suite
$5594 $192/night
24 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Oct 09, 2025 - Nov 02, 2025
29 Night Hawaii
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Guaymas, Mexico; Topolobampo, Mexico; Lore... San Diego
SAIL DATE: Dec 06, 2025 - Jan 04, 2026
Interior
$2504 $86/night
Oceanview
$2694 $92/night
Balcony
not available
Suite
$5944 $204/night
26 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Puer... Miami, Florida
SAIL DATE: Feb 27, 2026 - Mar 25, 2026
25 Night Hawaii
PORTS
San Diego; Avalon, Catalina Island, California; San Francisco; San Francisco; Astoria, Oreg... Vancouver
SAIL DATE: Apr 04, 2026 - Apr 29, 2026
35 Night Hawaii
PORTS
San Diego; Kahului, Maui; Hilo; Honolulu; Nawiliwili, Kauai; Kona, Hawaii, Us; Fanning Isla... San Diego
SAIL DATE: Feb 14, 2026 - Mar 21, 2026
27 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; Guaymas, Mexico; Topo... Miami, Florida
SAIL DATE: Feb 15, 2026 - Mar 14, 2026
Interior
$2939 $108/night
Oceanview
$3209 $118/night
Balcony
$4969 $184/night
Suite
not available
24 Night Hawaii
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Honolulu; Kahul... San Diego
SAIL DATE: Jan 02, 2027 - Jan 26, 2027
24 Night Hawaii
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Kahului, Maui; Hilo; Kona,... San Diego
SAIL DATE: Jan 03, 2026 - Jan 27, 2026
Interior
not available
Oceanview
$2929 $122/night
Balcony
$3979 $165/night
Suite
$8449 $352/night