Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
15 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; Acapulco; Puerto Quetzal, Guatemala; Puntarenas Puerto Cal... Miami, Florida
SAIL DATE: Feb 12, 2026 - Feb 27, 2026
15 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; Acapulco; Puerto Quetzal, Guatemala; Puntarenas Puerto Cal... Miami, Florida
SAIL DATE: Apr 03, 2027 - Apr 18, 2027
18 Night Hawaii
PORTS
San Diego; Hilo; Kona, Hawaii, Us; Kahului, Maui; Honolulu; Honolulu; Nawiliwili, Kauai; Ensenada; San Diego
SAIL DATE: Jan 27, 2026 - Feb 14, 2026
17 Night Hawaii
PORTS
San Diego; Honolulu; Kahului, Maui; Nawiliwili, Kauai; Hilo; Kona, Hawaii, Us; Ensenada; San Diego
SAIL DATE: Jan 09, 2027 - Jan 26, 2027
18 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Cabo San Lucas;... Vancouver
SAIL DATE: Mar 20, 2027 - Apr 07, 2027
18 Night Hawaii
PORTS
San Diego; Hilo; Kona, Hawaii, Us; Kahului, Maui; Nawiliwili, Kauai; Honolulu; Honolulu; Ensenada; San Diego
SAIL DATE: Nov 19, 2026 - Dec 07, 2026
Interior
$2064 $114/night
Oceanview
$2514 $139/night
Balcony
not available
Suite
$5284 $293/night
16 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; Acapulco; Huatulco, Mexico; Puerto Chiapas (Tapachula), Me... Fort Lauderdale
SAIL DATE: Oct 08, 2026 - Oct 24, 2026
16 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Oct 02, 2026 - Oct 18, 2026
