Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
14 Night Mexico
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Cabo San Lucas; PICHILINGU... San Diego
SAIL DATE: Oct 18, 2025 - Nov 01, 2025
Interior
not available
Oceanview
$1524 $108/night
Balcony
$1994 $142/night
Suite
$3704 $264/night
11 Night Mexico
PORTS
San Diego; Manzanillo; Puerto Vallarta; Mazatlan; PICHILINGUE (LA PAZ); Loreto, Mexico; Cab... San Diego
SAIL DATE: Dec 08, 2026 - Dec 19, 2026
14 Night Mexico
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Cabo San Lucas; PICHILINGU... San Diego
SAIL DATE: Mar 21, 2026 - Apr 04, 2026
14 Night Mexico
PORTS
San Diego; Ensenada; San Francisco; San Francisco; Santa Barbara, California; San Diego; Pu... San Diego
SAIL DATE: Oct 11, 2025 - Oct 25, 2025
Interior
not available
Oceanview
$1599 $114/night
Balcony
$1869 $133/night
Suite
not available
14 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; Acapulco; Puerto Quetzal, Guatemala; Panama City (Pct), Pan... Miami, Florida
SAIL DATE: Oct 18, 2025 - Nov 01, 2025
14 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Avalon, Catalin... Vancouver
SAIL DATE: Mar 28, 2026 - Apr 11, 2026
11 Night Mexico
PORTS
San Diego; Cabo San Lucas; Mazatlan; Puerto Vallarta; San Diego; Victoria; Vancouver
SAIL DATE: Mar 27, 2027 - Apr 07, 2027
12 Night Mexico
PORTS
San Diego; Cabo San Lucas; Loreto, Mexico; Guaymas, Mexico; Topolobampo, Mexico; PICHILINGU... San Diego
SAIL DATE: Dec 07, 2026 - Dec 19, 2026
Interior
$1404 $117/night
Oceanview
$1604 $133/night
Balcony
not available
Suite
$3204 $267/night
14 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Cabo San Lucas;... San Diego
SAIL DATE: Mar 20, 2027 - Apr 03, 2027
11 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; Mazatlan; Puerto Vallarta;... San Diego
SAIL DATE: Apr 07, 2026 - Apr 18, 2026
Interior
$1314 $119/night
Oceanview
$1464 $133/night
Balcony
not available
Suite
$3014 $274/night