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October 2025 San Diego 250 $ to 350 $
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October 2025 San Diego 250 $ to 350 $
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Best Cruises from San Diego

We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.

Very good price

Compared to other cruises

14 Night Mexico
Nieuw Amsterdam
3.9 "Good"

PORTS

San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Avalon, Catalin... San Diego

SAIL DATE:   Oct 25, 2025   -   Nov 08, 2025

Interior

$1354 $96/night
Price Curve

Oceanview

$1424 $101/night
Price Curve

Balcony

$1714 $122/night
Price Curve

Suite

$4244 $303/night
Price Curve

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Very good price

Compared to other cruises

14 Night Mexico
Nieuw Amsterdam
3.9 "Good"

PORTS

San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Cabo San Lucas; PICHILINGU... San Diego

SAIL DATE:   Oct 18, 2025   -   Nov 01, 2025

Interior

not available
Price Curve

Oceanview

$1524 $108/night
Price Curve

Balcony

$1994 $142/night
Price Curve

Suite

$3704 $264/night
Price Curve

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-1%

14 Night Panama Canal
Norwegian Jade
3.5 "Good"

PORTS

San Diego; Cabo San Lucas; Acapulco; Puerto Quetzal, Guatemala; Panama City (Pct), Pan... Miami, Florida

SAIL DATE:   Oct 18, 2025   -   Nov 01, 2025

Interior

$1439 $102/night
Price Curve

Oceanview

$1889 $134/night
Price Curve

Balcony

$3039 $217/night
Price Curve

Suite

$3539 $252/night
Price Curve

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Very good price

Compared to other cruises

7 Night Mexico
Nieuw Amsterdam
3.9 "Good"

PORTS

San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego

SAIL DATE:   Oct 18, 2025   -   Oct 25, 2025

Interior

$828 $118/night
Price Curve

Oceanview

$829 $118/night
Price Curve

Balcony

$929 $132/night
Price Curve

Suite

$1929 $275/night
Price Curve

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7 Night Mexico
Nieuw Amsterdam
3.9 "Good"

PORTS

San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego

SAIL DATE:   Oct 25, 2025   -   Nov 01, 2025

Interior

$829 $118/night
Price Curve

Oceanview

$879 $125/night
Price Curve

Balcony

$1179 $168/night
Price Curve

Suite

$2329 $332/night
Price Curve

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-8%

7 Night Mexico
Nieuw Amsterdam
3.9 "Good"

PORTS

San Diego; Ensenada; Cabo San Lucas; Puerto Vallarta; San Diego

SAIL DATE:   Oct 04, 2025   -   Oct 11, 2025

Interior

$984 $140/night
Price Curve

Oceanview

$1034 $147/night
Price Curve

Balcony

$1234 $176/night
Price Curve

Suite

$2334 $333/night
Price Curve

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4 Night Pacific Coastal
Koningsdam
3.9 "Good"

PORTS

San Diego; Santa Barbara, California; Avalon, Catalina Island, California; Ensenada; San Diego

SAIL DATE:   Oct 21, 2025   -   Oct 25, 2025

Interior

not available
Price Curve

Oceanview

$919 $229/night
Price Curve

Balcony

$1069 $267/night
Price Curve

Suite

$1169 $292/night
Price Curve

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Discover the best cruises from San Diego with our ultra-refined cruise search. Plus, save up to 70% off when you use our unmatched price prediction and free automatic price alerts! With cruisewatch.com, it’s simpler than ever to find your perfect cruise from San Diego and make it a vacation to remember. Explore expert tips and advice for all cruise lines, destinations, and cruise styles and set sail for savings from San Diego! Pack your bags and get ready to go - your dream cruise is now closer and better than ever!