Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
14 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Avalon, Catalin... San Diego
SAIL DATE: Oct 25, 2025 - Nov 08, 2025
14 Night Mexico
PORTS
San Diego; Ensenada; San Francisco; San Francisco; Santa Barbara, California; San Diego; Pu... San Diego
SAIL DATE: Oct 11, 2025 - Oct 25, 2025
7 Night Pacific Coastal
PORTS
San Diego; Ensenada; San Francisco; San Francisco; Santa Barbara, California; San Diego
SAIL DATE: Oct 11, 2025 - Oct 18, 2025
24 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Oct 09, 2025 - Nov 02, 2025
7 Night Mexico
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego
SAIL DATE: Oct 18, 2025 - Oct 25, 2025
7 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego
SAIL DATE: Oct 25, 2025 - Nov 01, 2025
17 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Oct 09, 2025 - Oct 26, 2025
4 Night Pacific Coastal
PORTS
San Diego; Santa Barbara, California; Avalon, Catalina Island, California; Ensenada; San Diego
SAIL DATE: Oct 21, 2025 - Oct 25, 2025
7 Night Mexico
PORTS
San Diego; Ensenada; Cabo San Lucas; Puerto Vallarta; San Diego
SAIL DATE: Oct 04, 2025 - Oct 11, 2025
14 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; Acapulco; Puerto Quetzal, Guatemala; Panama City (Pct), Pan... Miami, Florida
SAIL DATE: Oct 18, 2025 - Nov 01, 2025
