Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
15 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; Acapulco; Puerto Quetzal, Guatemala; Puntarenas Puerto Cal... Miami, Florida
SAIL DATE: Feb 12, 2026 - Feb 27, 2026
15 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; Acapulco; Puerto Quetzal, Guatemala; Puntarenas Puerto Cal... Miami, Florida
SAIL DATE: Apr 03, 2027 - Apr 18, 2027
14 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; Acapulco; Puerto Quetzal, Guatemala; Panama City (Pct), Pan... Miami, Florida
SAIL DATE: Oct 18, 2025 - Nov 01, 2025
7 Night Mexico
PORTS
San Diego; Cabo San Lucas; Mazatlan; Puerto Vallarta; San Diego
SAIL DATE: Dec 26, 2026 - Jan 02, 2027
7 Night Mexico
PORTS
San Diego; Cabo San Lucas; Mazatlan; Puerto Vallarta; San Diego
SAIL DATE: Dec 19, 2026 - Dec 26, 2026
16 Night N-A
PORTS
San Diego; Honolulu; Kailua-Kona; Nuku Hiva, Marquesas; Rangiroa, French Polynesia; M... Papeete, Tahiti
SAIL DATE: Mar 07, 2026 - Mar 23, 2026
Interior
not available
Oceanview
not available
Balcony
$4599 $287/night
Suite
$9199 $574/night