Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
14 Night Mexico
PORTS
San Diego; Avalon, Catalina Island, California; San Francisco; San Francisco; Ensenada; San... San Diego
SAIL DATE: Nov 01, 2025 - Nov 15, 2025
28 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 29, 2025
14 Night Mexico
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Cabo San Lucas; PICHILINGU... San Diego
SAIL DATE: Nov 08, 2025 - Nov 22, 2025
17 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 18, 2025
14 Night Mexico
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Cabo San Lucas; PICHILINGU... San Diego
SAIL DATE: Oct 18, 2025 - Nov 01, 2025
14 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Puerto Vallarta... San Diego
SAIL DATE: Nov 15, 2025 - Nov 29, 2025
5 Night Pacific Coastal
PORTS
San Diego; San Francisco; Vancouver
SAIL DATE: Apr 27, 2026 - May 02, 2026
4 Night Pacific Coastal
PORTS
San Diego; Avalon, Catalina Island, California; Vancouver
SAIL DATE: Apr 20, 2026 - Apr 24, 2026
29 Night Hawaii
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Guaymas, Mexico; Topolobampo, Mexico; Lore... San Diego
SAIL DATE: Dec 06, 2025 - Jan 04, 2026
Interior
$2504 $86/night
Oceanview
$2694 $92/night
Balcony
not available
Suite
$5944 $204/night
4 Night Pacific Coastal
PORTS
San Diego; Santa Barbara, California; Avalon, Catalina Island, California; Ensenada; San Diego
SAIL DATE: Oct 21, 2025 - Oct 25, 2025
