Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
14 Night Mexico
PORTS
San Diego; Avalon, Catalina Island, California; San Francisco; San Francisco; Ensenada; San... San Diego
SAIL DATE: Nov 01, 2025 - Nov 15, 2025
14 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Avalon, Catalin... San Diego
SAIL DATE: Oct 25, 2025 - Nov 08, 2025
7 Night Pacific Coastal
PORTS
San Diego; Avalon, Catalina Island, California; San Francisco; San Francisco; Ensenada; San Diego
SAIL DATE: Nov 01, 2025 - Nov 08, 2025
14 Night Mexico
PORTS
San Diego; Ensenada; San Francisco; San Francisco; Santa Barbara, California; San Diego; Pu... San Diego
SAIL DATE: Oct 11, 2025 - Oct 25, 2025
28 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 29, 2025
14 Night Mexico
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Cabo San Lucas; PICHILINGU... San Diego
SAIL DATE: Nov 08, 2025 - Nov 22, 2025
17 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 18, 2025
5 Night Pacific Coastal
PORTS
San Diego; San Francisco; Vancouver
SAIL DATE: Apr 27, 2026 - May 02, 2026
7 Night Pacific Coastal
PORTS
San Diego; Ensenada; San Francisco; San Francisco; Santa Barbara, California; San Diego
SAIL DATE: Oct 11, 2025 - Oct 18, 2025
11 Night Mexico
PORTS
San Diego; Puerto Vallarta; Manzanillo; Mazatlan; Loreto, Mexico; PICHILINGUE (LA PAZ); Cab... San Diego
SAIL DATE: Dec 09, 2025 - Dec 20, 2025
