Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
12 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Guaymas, Mexico; Topolobampo, Mexico; Lore... San Diego
SAIL DATE: Dec 06, 2025 - Dec 18, 2025
Interior
$1174 $97/night
Oceanview
$1224 $102/night
Balcony
not available
Suite
$2574 $214/night
14 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; Acapulco; Puerto Quetzal, Guatemala; Panama City (Pct), Pan... Miami, Florida
SAIL DATE: Oct 18, 2025 - Nov 01, 2025
11 Night Mexico
PORTS
San Diego; Cabo San Lucas; Mazatlan; Puerto Vallarta; San Diego; Avalon, Catalina Island, C... Vancouver
SAIL DATE: Apr 25, 2026 - May 06, 2026
Interior
$1134 $103/night
Oceanview
$1284 $116/night
Balcony
not available
Suite
$2834 $257/night
12 Night Mexico
PORTS
San Diego; Cabo San Lucas; Loreto, Mexico; Guaymas, Mexico; Topolobampo, Mexico; PICHILINGU... San Diego
SAIL DATE: Dec 07, 2026 - Dec 19, 2026
Interior
$1404 $117/night
Oceanview
$1604 $133/night
Balcony
not available
Suite
$3204 $267/night
11 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; Mazatlan; Puerto Vallarta;... San Diego
SAIL DATE: Apr 07, 2026 - Apr 18, 2026
Interior
$1314 $119/night
Oceanview
$1464 $133/night
Balcony
not available
Suite
$3014 $274/night
14 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; San Diego; Cabo San Lucas;... San Diego
SAIL DATE: Apr 18, 2026 - May 02, 2026
Interior
$1679 $119/night
Oceanview
$1849 $132/night
Balcony
not available
Suite
$3769 $269/night
12 Night Mexico
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; Guaymas, Mexico; Topolobam... San Diego
SAIL DATE: Feb 15, 2026 - Feb 27, 2026
14 Night Mexico
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Cabo San Lucas; PICHILINGU... San Diego
SAIL DATE: Jan 16, 2027 - Jan 30, 2027
13 Night Mexico
PORTS
San Diego; Cabo San Lucas; Loreto, Mexico; Guaymas, Mexico; Topolobampo, Mexico; PICHILINGU... San Diego
SAIL DATE: Apr 04, 2027 - Apr 17, 2027
Interior
$1764 $135/night
Oceanview
$1994 $153/night
Balcony
not available
Suite
$3884 $298/night
11 Night Mexico
PORTS
San Diego; Cabo San Lucas; Loreto, Mexico; Guaymas, Mexico; Topolobampo, Mexico; PICHILINGU... San Diego
SAIL DATE: Jan 03, 2027 - Jan 14, 2027
Interior
$1499 $136/night
Oceanview
$1699 $154/night
Balcony
not available
Suite
$3299 $299/night