Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
28 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 29, 2025
24 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Oct 09, 2025 - Nov 02, 2025
26 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Puer... Miami, Florida
SAIL DATE: Feb 27, 2026 - Mar 25, 2026
27 Night Panama Canal
PORTS
San Diego; Cabo San Lucas; PICHILINGUE (LA PAZ); Loreto, Mexico; Guaymas, Mexico; Topo... Miami, Florida
SAIL DATE: Feb 15, 2026 - Mar 14, 2026
Interior
$3094 $114/night
Oceanview
$3384 $125/night
Balcony
$5374 $199/night
Suite
not available
32 Night Caribbean
PORTS
San Diego; Ensenada; Cabo San Lucas (Baja California Sur); Puerto Vallarta; Acajutla, E... New York City
SAIL DATE: Aug 24, 2026 - Sep 25, 2026
Interior
not available
Oceanview
$13740 $429/night
Balcony
$16260 $508/night
Suite
$18330 $572/night