Best Cruises from San Diego
We've found the Best Cruises from San Diego for the best prices! Easily compare sailings and find out when to book with our unique cruise search.
28 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 29, 2025
17 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Nov 01, 2025 - Nov 18, 2025
4 Night Pacific Coastal
PORTS
San Diego; Avalon, Catalina Island, California; Vancouver
SAIL DATE: Apr 20, 2026 - Apr 24, 2026
24 Night Panama Canal
PORTS
San Diego; Puerto Vallarta; Huatulco, Mexico; Puerto Chiapas (Tapachula), Mexico; Pue... Fort Lauderdale
SAIL DATE: Oct 09, 2025 - Nov 02, 2025
11 Night Mexico
PORTS
San Diego; Manzanillo; Puerto Vallarta; Mazatlan; PICHILINGUE (LA PAZ); Loreto, Mexico; Cab... San Diego
SAIL DATE: Dec 08, 2026 - Dec 19, 2026
14 Night Mexico
PORTS
San Diego; Puerto Vallarta; Mazatlan; Cabo San Lucas; San Diego; Cabo San Lucas; PICHILINGU... San Diego
SAIL DATE: Mar 21, 2026 - Apr 04, 2026
11 Night Mexico
PORTS
San Diego; Manzanillo; Puerto Vallarta; Mazatlan; PICHILINGUE (LA PAZ); Loreto, Mexico; Cab... San Diego
SAIL DATE: Oct 20, 2026 - Oct 31, 2026
25 Night Hawaii
PORTS
San Diego; Avalon, Catalina Island, California; San Francisco; San Francisco; Astoria, Oreg... Vancouver
SAIL DATE: Apr 04, 2026 - Apr 29, 2026
17 Night Hawaii
PORTS
San Diego; Kahului, Maui; Hilo; Kona, Hawaii, Us; Honolulu; Nawiliwili, Kauai; Ensenada; San Diego
SAIL DATE: Jan 10, 2026 - Jan 27, 2026
